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Search Results for " dopamine beta-hydroxylase "

Targets

11

Compounds

4

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T19654 Guanoclor VATENSOL Others
Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.
T13383 Zamicastat BIA 5-1058 BCRP , Hydroxylase , P-gp
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73.8 μM and 17.0 μM, respectively).
T6604 Nepicastat hydrochloride Nepicastat HCl,RS-25560-197 hydrochloride,SYN-117 hydrochloride,Nepicastat (SYN-117) HCl Hydroxylase
Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.The affinity of Nepicasta...
T30615 Bupicomide Hydroxylase
Bupicomide is a dopamine beta hydroxylase inhibitor with antihypertensive and vasodilatory activity that reduces 14C-norepinephrine biosynthesis of 14C-dopamine and can be used to study hypertension.
T11238L Etamicastat hydrochloride BIA 5-453 hydrochloride Dehydrogenase
Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.
T50049 4-Methylhistamine hydrochloride Others
4-Methylhistamine hydrochloride has been shown to inhibit the activity of copper-dependent enzymes such as tyrosinase and dopamine beta-hydroxylase and has also been shown to modulate the expression of genes involved in ...
T71936 Phenylthiazolylthiourea
Phenylthiazolylthiourea ia a dopamine-beta-hydroxylase inhibitor.
T69568 FLA-63
FLA-63 is a dopamine-beta-hydroxylase (DBH)-inhibitor and an inhibitor of the last step of noradrenaline biosynthesis.
T70209 Nepicastat hydrochloride monohydrate
Nepicastat hydrochloride monohydrate is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.
T23848 Calcium Fusarate
Calcium Fumarate is an inhibitor of dopamine beta-hydroxylase. It also inhibited cell proliferation and DNA synthesis.
T60633 Nepicastat
Nepicastat (SYN117) is a selective, potent, and orally active dopamine-beta-hydroxylase inhibitor which can cross the blood-brain barrier (BBB). Nepicastat (SYN117) produces concentration-dependent inhibition of bovine a...
Cat No. Product Name Synonyms Targets
T6S0923 Hypericin Hypericine,Cyclosan Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...
TN2252 Syrosingopine Dopamine Receptor
Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase inhibitor.
T2S1778 DL-Goitrin Goitrin Others
DL-Goitrin is a potent antithyroid compound found naturally in crucifers. DL-Goitrin is responsible for the induction of glutathione S-transferases. DL-Goitrin is a moderate inhibitor of purified bovine adrenal dopamine ...
T25900 Oosponol Lenzitin
Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03852 Dopamine beta-Hydroxylase Protein, Human, Recombinant (His) Human HEK293 Cells
DBH is a 29 kDa copper-containing oxygenase. It can be detected in noradrenergic nerve terminals of the central and peripheral nervous systems, and is also expressed in chromaffin cells of the adrenal medulla. DBH conta...
TargetMol