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Cat No. | Product Name | Synonyms | Targets |
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T19654 | Guanoclor | VATENSOL | Others |
Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes. | |||
T13383 | Zamicastat | BIA 5-1058 | BCRP , Hydroxylase , P-gp |
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73.8 μM and 17.0 μM, respectively). | |||
T6604 | Nepicastat hydrochloride | Nepicastat HCl,RS-25560-197 hydrochloride,SYN-117 hydrochloride,Nepicastat (SYN-117) HCl | Hydroxylase |
Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.The affinity of Nepicasta... | |||
T30615 | Bupicomide | Hydroxylase | |
Bupicomide is a dopamine beta hydroxylase inhibitor with antihypertensive and vasodilatory activity that reduces 14C-norepinephrine biosynthesis of 14C-dopamine and can be used to study hypertension. | |||
T11238L | Etamicastat hydrochloride | BIA 5-453 hydrochloride | Dehydrogenase |
Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension. | |||
T50049 | 4-Methylhistamine hydrochloride | Others | |
4-Methylhistamine hydrochloride has been shown to inhibit the activity of copper-dependent enzymes such as tyrosinase and dopamine beta-hydroxylase and has also been shown to modulate the expression of genes involved in ... | |||
T71936 | Phenylthiazolylthiourea | ||
Phenylthiazolylthiourea ia a dopamine-beta-hydroxylase inhibitor. | |||
T69568 | FLA-63 | ||
FLA-63 is a dopamine-beta-hydroxylase (DBH)-inhibitor and an inhibitor of the last step of noradrenaline biosynthesis. | |||
T70209 | Nepicastat hydrochloride monohydrate | ||
Nepicastat hydrochloride monohydrate is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. | |||
T23848 | Calcium Fusarate | ||
Calcium Fumarate is an inhibitor of dopamine beta-hydroxylase. It also inhibited cell proliferation and DNA synthesis. | |||
T60633 | Nepicastat | ||
Nepicastat (SYN117) is a selective, potent, and orally active dopamine-beta-hydroxylase inhibitor which can cross the blood-brain barrier (BBB). Nepicastat (SYN117) produces concentration-dependent inhibition of bovine a... |
Cat No. | Product Name | Synonyms | Targets |
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T6S0923 | Hypericin | Hypericine,Cyclosan | Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC |
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL... | |||
TN2252 | Syrosingopine | Dopamine Receptor | |
Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase inhibitor. | |||
T2S1778 | DL-Goitrin | Goitrin | Others |
DL-Goitrin is a potent antithyroid compound found naturally in crucifers. DL-Goitrin is responsible for the induction of glutathione S-transferases. DL-Goitrin is a moderate inhibitor of purified bovine adrenal dopamine ... | |||
T25900 | Oosponol | Lenzitin | |
Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects. |
Cat No. | Product Name | Species | Expression System |
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TMPY-03852 | Dopamine beta-Hydroxylase Protein, Human, Recombinant (His) | Human | HEK293 Cells |
DBH is a 29 kDa copper-containing oxygenase. It can be detected in noradrenergic nerve terminals of the central and peripheral nervous systems, and is also expressed in chromaffin cells of the adrenal medulla. DBH conta... |